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Subinhibitory Concentrations of the Deformylase Inhibitor Actinonin Increase Bacterial Release of Neutrophil-Activating Peptides: a New Approach to Antimicrobial Chemotherapy
Bacterial protein synthesis starts with a formylated methionine residue, and this residue is sequentially cleaved away by a unique peptide deformylase (PDF) and a methionine aminopeptidase to generate mature proteins. The formylation-deformylation of proteins is a unique hallmark of bacterial metabo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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American Society for Microbiology
2003
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166101/ https://ncbi.nlm.nih.gov/pubmed/12878517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2545-2550.2003 |
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