In Vivo Antimalarial Activities of Mono- and Bis Quaternary Ammonium Salts Interfering with Plasmodium Phospholipid Metabolism

We previously showed that quaternary ammonium salts have potent antimalarial activities against the blood stage of drug-resistant Plasmodium falciparum. In the present study, 13 compounds of this series were comparatively assessed in murine in vivo malarial models. Mice infected with Plasmodium berg...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Ancelin, Marie L., Calas, Michèle, Bonhoure, Anne, Herbute, Serge, Vial, Henri J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Experimental Therapeutics
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878525/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2598-2605.2003
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