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In Vivo Antimalarial Activities of Mono- and Bis Quaternary Ammonium Salts Interfering with Plasmodium Phospholipid Metabolism

We previously showed that quaternary ammonium salts have potent antimalarial activities against the blood stage of drug-resistant Plasmodium falciparum. In the present study, 13 compounds of this series were comparatively assessed in murine in vivo malarial models. Mice infected with Plasmodium berg...

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Hlavní autoři: Ancelin, Marie L., Calas, Michèle, Bonhoure, Anne, Herbute, Serge, Vial, Henri J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC166095/
https://ncbi.nlm.nih.gov/pubmed/12878525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2598-2605.2003
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