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Potent Inhibitors of Plasmodium Phospholipid Metabolism with a Broad Spectrum of In Vitro Antimalarial Activities

We characterized the potent in vitro antimalarial activity and biologic assessment of 13 phospholipid polar head analogs on a comparative basis. There was a positive relationship between the abilities of the drugs to inhibit parasite growth in culture and their abilities to specifically inhibit phos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ancelin, Marie L., Calas, Michèle, Vidal-Sailhan, Valérie, Herbuté, Serge, Ringwald, Pascal, Vial, Henri J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC166094/
https://ncbi.nlm.nih.gov/pubmed/12878524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2590-2597.2003
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