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Potent Inhibitors of Plasmodium Phospholipid Metabolism with a Broad Spectrum of In Vitro Antimalarial Activities

We characterized the potent in vitro antimalarial activity and biologic assessment of 13 phospholipid polar head analogs on a comparative basis. There was a positive relationship between the abilities of the drugs to inhibit parasite growth in culture and their abilities to specifically inhibit phos...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Ancelin, Marie L., Calas, Michèle, Vidal-Sailhan, Valérie, Herbuté, Serge, Ringwald, Pascal, Vial, Henri J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
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Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166094/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878524/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2590-2597.2003
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