Reduced Release of Pneumolysin by Streptococcus pneumoniae In Vitro and In Vivo after Treatment with Nonbacteriolytic Antibiotics in Comparison to Ceftriaxone
Pneumolysin, a virulence factor of Streptococcus pneumoniae with cytotoxic and proinflammatory activities, occurs at concentrations from 0.85 to 180 ng/ml in cerebrospinal fluid (CSF) of meningitis patients. In pneumococcal cultures and in a rabbit meningitis model, the concentrations of pneumolysin...
Sparad:
| I publikationen: | Antimicrob Agents Chemother |
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| Huvudupphov: | , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
American Society for Microbiology (ASM)
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2649-2654.2003 |
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