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Activities of Mutant Prevention Concentration-Targeted Moxifloxacin and Levofloxacin against Streptococcus pneumoniae in an In Vitro Pharmacodynamic Model

The differential effects of moxifloxacin and levofloxacin on the development of resistance in four Streptococcus pneumoniae isolates were examined by using an in vitro pharmacodynamic model. Therapeutic regimens (moxifloxacin: peak, 4.5 μg/ml; half-life [t(1/2)], 12 h; and levofloxacin: peak, 6 μg/m...

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書誌詳細
主要な著者: Allen, George P., Kaatz, Glenn W., Rybak, Michael J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC166082/
https://ncbi.nlm.nih.gov/pubmed/12878526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2606-2614.2003
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