Activities of Mutant Prevention Concentration-Targeted Moxifloxacin and Levofloxacin against Streptococcus pneumoniae in an In Vitro Pharmacodynamic Model

The differential effects of moxifloxacin and levofloxacin on the development of resistance in four Streptococcus pneumoniae isolates were examined by using an in vitro pharmacodynamic model. Therapeutic regimens (moxifloxacin: peak, 4.5 μg/ml; half-life [t(1/2)], 12 h; and levofloxacin: peak, 6 μg/m...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Allen, George P., Kaatz, Glenn W., Rybak, Michael J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Experimental Therapeutics
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166082/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2606-2614.2003
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