Activities of Mutant Prevention Concentration-Targeted Moxifloxacin and Levofloxacin against Streptococcus pneumoniae in an In Vitro Pharmacodynamic Model

The differential effects of moxifloxacin and levofloxacin on the development of resistance in four Streptococcus pneumoniae isolates were examined by using an in vitro pharmacodynamic model. Therapeutic regimens (moxifloxacin: peak, 4.5 μg/ml; half-life [t(1/2)], 12 h; and levofloxacin: peak, 6 μg/m...

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Autores principales: Allen, George P., Kaatz, Glenn W., Rybak, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC166082/
https://ncbi.nlm.nih.gov/pubmed/12878526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2606-2614.2003
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