Molecular Mechanisms of Itraconazole Resistance in Candida dubliniensis

It has previously been shown that overexpression of the CdMDR1 gene is a major contributor to resistance in fluconazole-resistant isolates of Candida dubliniensis. However, since CdMdr1p does not mediate transport of other azole drugs such as itraconazole, we investigated the molecular mechanisms of...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Pinjon, Emmanuelle, Moran, Gary P., Jackson, Colin J., Kelly, Steven L., Sanglard, Dominique, Coleman, David C., Sullivan, Derek J.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2003
Teme:	Mechanisms of Resistance
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166077/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878500/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2424-2437.2003
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