Molecular Mechanisms of Itraconazole Resistance in Candida dubliniensis

It has previously been shown that overexpression of the CdMDR1 gene is a major contributor to resistance in fluconazole-resistant isolates of Candida dubliniensis. However, since CdMdr1p does not mediate transport of other azole drugs such as itraconazole, we investigated the molecular mechanisms of...

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Autori principali: Pinjon, Emmanuelle, Moran, Gary P., Jackson, Colin J., Kelly, Steven L., Sanglard, Dominique, Coleman, David C., Sullivan, Derek J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC166077/
https://ncbi.nlm.nih.gov/pubmed/12878500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2424-2437.2003
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