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Thiosemicarbazole (Thiacetazone-Like) Compound with Activity against Mycobacterium avium in Mice
In vitro screening of thiacetazone derivatives indicated that two derivatives, SRI-286 and SRI-224, inhibited a panel of 25 Mycobacterium avium complex (MAC) isolates at concentrations of 2 μg/ml or lower. In mice, SRI-224 and thiacetazone had no significant activity against the MAC in livers and sp...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166073/ https://ncbi.nlm.nih.gov/pubmed/12878542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2685-2687.2003 |
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