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DNA Immunization with the Cysteine-Rich Interdomain Region 1 of the Plasmodium falciparum Variant Antigen Elicits Limited Cross-Reactive Antibody Responses

The variant surface antigens of Plasmodium falciparum are an important component of naturally acquired immunity and an important vaccine target. However, these proteins appear to elicit primarily variant-specific antibodies. We tested if naked DNA immunization can elicit more cross-reactive antibody...

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Detalhes bibliográficos
Main Authors: Baruch, Dror I., Gamain, Benoit, Miller, Louis H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166004/
https://ncbi.nlm.nih.gov/pubmed/12874333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4536-4543.2003
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