DNA Immunization with the Cysteine-Rich Interdomain Region 1 of the Plasmodium falciparum Variant Antigen Elicits Limited Cross-Reactive Antibody Responses

The variant surface antigens of Plasmodium falciparum are an important component of naturally acquired immunity and an important vaccine target. However, these proteins appear to elicit primarily variant-specific antibodies. We tested if naked DNA immunization can elicit more cross-reactive antibody...

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Detalles Bibliográficos
Autores principales: Baruch, Dror I., Gamain, Benoit, Miller, Louis H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC166004/
https://ncbi.nlm.nih.gov/pubmed/12874333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4536-4543.2003
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