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Biochemical properties of phosphonoacetate and thiophosphonoacetate oligodeoxyribonucleotides

Phosphorus-modified phosphonoacetate and thiophosphonoacetate oligodeoxyribonucleotides were chemically synthesized and their biochemical properties evaluated. Under physiological pH, these DNA analogs possess negative charge and form stable, complementary A-like DNA:RNA heteroduplexes when analyzed...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Sheehan, David, Lunstad, Benjamin, Yamada, Christina M., Stell, Brian G., Caruthers, Marvin H., Dellinger, Douglas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2003
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165954/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12853628/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg439
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