Glycerol replacement corrects defective skin hydration, elasticity, and barrier function in aquaporin-3-deficient mice
Mice deficient in the epidermal water/glycerol transporter aquaporin-3 (AQP3) have reduced stratum corneum (SC) hydration and skin elasticity, and impaired barrier recovery after SC removal. SC glycerol content is reduced 3-fold in AQP3 null mice, whereas SC structure, protein/lipid composition, and...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165880/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12771381/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1230416100 |
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