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Glycerol replacement corrects defective skin hydration, elasticity, and barrier function in aquaporin-3-deficient mice
Mice deficient in the epidermal water/glycerol transporter aquaporin-3 (AQP3) have reduced stratum corneum (SC) hydration and skin elasticity, and impaired barrier recovery after SC removal. SC glycerol content is reduced 3-fold in AQP3 null mice, whereas SC structure, protein/lipid composition, and...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165880/ https://ncbi.nlm.nih.gov/pubmed/12771381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1230416100 |
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