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Transcriptional profiling of the Sonic hedgehog response: A critical role for N-myc in proliferation of neuronal precursors
Cerebellar granule cells are the most abundant neurons in the brain, and granule cell precursors (GCPs) are a common target of transformation in the pediatric brain tumor medulloblastoma. Proliferation of GCPs is regulated by the secreted signaling molecule Sonic hedgehog (Shh), but the mechanisms b...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165875/ https://ncbi.nlm.nih.gov/pubmed/12777630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0832317100 |
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