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UV wavelength-dependent regulation of transcription-coupled nucleotide excision repair in p53-deficient human cells

Nucleotide excision repair (NER) prevents skin cancer by eliminating highly genotoxic cyclobutane pyrimidine dimers (CPDs) induced in DNA by the UVB component of sunlight. NER consists of two distinct but overlapping subpathways, i.e., global NER, which removes CPD from the genome overall, and trans...

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Autors principals: Mathonnet, Géraldine, Léger, Caroline, Desnoyers, Julie, Drouin, Régen, Therrien, Jean-Philippe, Drobetsky, Elliot A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC165856/
https://ncbi.nlm.nih.gov/pubmed/12775760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232161100
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