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Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution

We developed a method for genome-wide mapping of DNA excision repair named XR-seq (excision repair sequencing). Human nucleotide excision repair generates two incisions surrounding the site of damage, creating an ∼30-mer. In XR-seq, this fragment is isolated and subjected to high-throughput sequenci...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Hu, Jinchuan, Adar, Sheera, Selby, Christopher P., Lieb, Jason D., Sancar, Aziz
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421983/
https://ncbi.nlm.nih.gov/pubmed/25934506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.261271.115
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