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3D electron microscopy reveals the variable deposition and protein dynamics of the peripheral pyruvate dehydrogenase component about the core

Cryo-electron microscopy was exploited to reveal and study the influence of pyruvate dehydrogenase (E(1)) occupancy on the conformational states of the Saccharomyces cerevisiae pyruvate dehydrogenase complex (PDC). Structures representative of PDC preparations with ≈40% and full E(1) occupancy were...

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Detalhes bibliográficos
Main Authors: Gu, Yingqi, Zhou, Z. Hong, McCarthy, Diane B., Reed, Lester J., Stoops, James K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165822/
https://ncbi.nlm.nih.gov/pubmed/12756305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0732060100
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