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AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

Leukemia-specific AML1/ETO transcripts are detectable in most patients with t(8;21) acute myelogenous leukemia (AML) in long-term remission. To understand the inconsistency between the clinical cure and the presence of “residual disease” at a molecular level, we separated and identified the cells ex...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Miyamoto, Toshihiro, Weissman, Irving L., Akashi, Koichi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16578/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10861016/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.13.7521
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