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Competition between MutY and Mismatch Repair at A · C Mispairs In Vivo

We show that the MutY protein competes with the MutS-dependent mismatch repair system to process at least some A · C mispairs in vivo, converting them to G · C pairs. In the presence of an increased dCTP pool resulting from the loss of nucleotide diphosphate kinase, the frequency of A · T→G · C tran...

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Bibliografiske detaljer
Main Authors: Kim, Mandy, Huang, Tiffany, Miller, Jeffrey H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC165771/
https://ncbi.nlm.nih.gov/pubmed/12867475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.15.4626-4629.2003
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