IS981-Mediated Adaptive Evolution Recovers Lactate Production by ldhB Transcription Activation in a Lactate Dehydrogenase-Deficient Strain of Lactococcus lactis

Lactococcus lactis NZ9010 in which the las operon-encoded ldh gene was replaced with an erythromycin resistance gene cassette displayed a stable phenotype when grown under aerobic conditions, and its main end products of fermentation under these conditions were acetate and acetoin. However, under an...

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Hauptverfasser: Bongers, Roger S., Hoefnagel, Marcel H. N., Starrenburg, Marjo J. C., Siemerink, Marco A. J., Arends, John G. A., Hugenholtz, Jeroen, Kleerebezem, Michiel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Genetics and Molecular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC165757/
https://ncbi.nlm.nih.gov/pubmed/12867459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.15.4499-4507.2003
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