The N-CoR/Histone Deacetylase 3 Complex Is Required for Repression by Thyroid Hormone Receptor

Nuclear receptor corepressors (N-CoR) and silencing mediator for retinoid and thyroid receptors (SMRT) have both been implicated in thyroid hormone receptor (TR)-mediated repression. Here we show that endogenous N-CoR, TBL1, and histone deacetylase 3 (HDAC3), but not HDAC1, -2, or -4, are recruited...

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Bibliographic Details
Main Authors: Ishizuka, Takahiro, Lazar, Mitchell A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC165720/
https://ncbi.nlm.nih.gov/pubmed/12861000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.15.5122-5131.2003
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