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Prion-derived copper-binding peptide fragments catalyze the generation of superoxide anion in the presence of aromatic monoamines

Objectives: Studies have proposed two opposing roles for copper-bound forms of prion protein (PrP) as an anti-oxidant supporting the neuronal functions and as a pro-oxidant leading to neurodegenerative process involving the generation of reactive oxygen species. The aim of this study is to test the...

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Autor principal: Kawano, Tomonori
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1657085/
https://ncbi.nlm.nih.gov/pubmed/17200692
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