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Intrarenal Oxidative Stress and Augmented Angiotensinogen are Precedent to Renal Injury in Zucker Diabetic Fatty Rats

The Zucker diabetic fatty (ZDF) rat is a model of type II diabetes and metabolic syndrome based on impaired glucose tolerance caused by the inherited insulin-resistance gene. The ZDF rat exhibits progressive nephropathy; however, the detailed mechanisms have remained unclear. This study was performe...

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Detalhes bibliográficos
Main Authors: Suzaki, Yuki, Ozawa, Yuri, Kobori, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1657083/
https://ncbi.nlm.nih.gov/pubmed/17200690
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