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A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death

Legionella pneumophila requires the Dot/Icm protein translocation system to replicate within host cells as a critical component of Legionnaire's pneumonia. None of the known individual substrates of the translocator have been shown to be essential for intracellular replication. We demonstrate h...

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Autors principals: Laguna, Rita K., Creasey, Elizabeth A., Li, Zhiru, Valtz, Nicole, Isberg, Ralph R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1656969/
https://ncbi.nlm.nih.gov/pubmed/17124169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609012103
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