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Keratin 20 Helps Maintain Intermediate Filament Organization in Intestinal Epithelia

Of the >20 epithelial keratins, keratin 20 (K20) has an unusual distribution and is poorly studied. We began to address K20 function, by expressing human wild-type and Arg80→His (R80H) genomic (18 kb) and cDNA K20 in cells and mice. Arg80 of K20 is conserved in most keratins, and its mutation in...

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Main Authors: Zhou, Qin, Toivola, Diana M., Feng, Ningguo, Greenberg, Harry B., Franke, Werner W., Omary, M. Bishr
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC165690/
https://ncbi.nlm.nih.gov/pubmed/12857878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-02-0059
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