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Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles
Nek2A is a cell cycle-regulated kinase of the never in mitosis A (NIMA) family that is highly enriched at the centrosome. One model for Nek2A function proposes that it regulates cohesion between the mother and daughter centriole through phosphorylation of C-Nap1, a large coiled-coil protein that loc...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165683/ https://ncbi.nlm.nih.gov/pubmed/12857871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-02-0108 |
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