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Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles

Nek2A is a cell cycle-regulated kinase of the never in mitosis A (NIMA) family that is highly enriched at the centrosome. One model for Nek2A function proposes that it regulates cohesion between the mother and daughter centriole through phosphorylation of C-Nap1, a large coiled-coil protein that loc...

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Autors principals: Faragher, Alison J., Fry, Andrew M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC165683/
https://ncbi.nlm.nih.gov/pubmed/12857871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-02-0108
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