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Structure of a trapped endonuclease III–DNA covalent intermediate
Nearly all cells express proteins that confer resistance to the mutagenic effects of oxidative DNA damage. The primary defense against the toxicity of oxidative nucleobase lesions in DNA is the base-excision repair (BER) pathway. Endonuclease III (EndoIII) is a [4Fe–4S] cluster-containing DNA glycos...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165637/ https://ncbi.nlm.nih.gov/pubmed/12840008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg311 |
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