Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system

In the eukaryotic cytosol, Hsp70 and Hsp90 cooperate with various co-chaperone proteins in the folding of a growing set of substrates, including the glucocorticoid receptor (GR). Here, we analyse the function of the co-chaperone Tpr2, which contains two chaperone-binding TPR domains and a DnaJ homol...

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Dades bibliogràfiques

Publicat a:	EMBO J
Autors principals:	Brychzy, Alexander, Rein, Theo, Winklhofer, Konstanze F., Hartl, F.Ulrich, Young, Jason C., Obermann, Wolfgang M.J.
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Publishing Group 2003
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12853476/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg362
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