Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway

Nbk/Bik (natural born killer/Bcl-2-interacting killer) is a tissue-specific BH3-only protein whose molecular function is still largely unknown. To investigate the mechanism of Nbk action, we established a single- vector adenoviral system based on the Tet-off conditional expression of Nbk. Upon Nbk e...

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Detalles Bibliográficos

Publicado en:	EMBO J
Principais autores:	Gillissen, Bernhard, Essmann, Frank, Graupner, Vilma, Stärck, Lilian, Radetzki, Silke, Dörken, Bernd, Schulze-Osthoff, Klaus, Daniel, Peter T.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Publishing Group 2003
Assuntos:	Articles
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12853473/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg343
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