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The stereospecificity of flobufen metabolism in isolated guinea pig hepatocytes
BACKGROUND: Flobufen (F) is an original nonsteroidal anti-inflammatory drug with one center of chirality. 4-Dihydroflobufen (DHF), compound with two chiral centers, is the main metabolite of F in microsomes and cytosol in all standard laboratory animals. This work describes the biotransformation of...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165433/ https://ncbi.nlm.nih.gov/pubmed/12791169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-3-5 |
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