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The centrosome and cell proliferation

Centrosomes are frequently amplified in cancer cells. Increased numbers of centrosomes can give rise to multipolar spindles in mitosis, and thereby lead to the formation of aneuploid daughter cells. However, whether centrosome amplification is a cause or a consequence of cancer is unclear. In contra...

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Autors principals: Srsen, Vlastimil, Merdes, Andreas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1654144/
https://ncbi.nlm.nih.gov/pubmed/17109756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-1-26
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