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The centrosome and cell proliferation

Centrosomes are frequently amplified in cancer cells. Increased numbers of centrosomes can give rise to multipolar spindles in mitosis, and thereby lead to the formation of aneuploid daughter cells. However, whether centrosome amplification is a cause or a consequence of cancer is unclear. In contra...

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Detalhes bibliográficos
Main Authors: Srsen, Vlastimil, Merdes, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1654144/
https://ncbi.nlm.nih.gov/pubmed/17109756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-1-26
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