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Acetylation of MEK2 and IκB kinase (IKK) activation loop residues by YopJ inhibits signaling

To overcome host defenses, bacterial pathogens of the genus Yersinia inject specific effector proteins into colonized mammalian cells. One such virulence factor, YopJ, inhibits the host inflammatory response and induces apoptosis of immune cells by blocking multiple signaling pathways, including the...

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Detalhes bibliográficos
Main Authors: Mittal, Rohit, Peak-Chew, Sew-Yeu, McMahon, Harvey T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1654131/
https://ncbi.nlm.nih.gov/pubmed/17116858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608995103
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