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Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function
Tipin is a mammalian protein that interacts with Timeless, which plays a role in DNA damage checkpoint responses. Here, we show that Tipin is a nuclear protein that associates with the replicative helicase and protects cells against genotoxic agents. Tipin is required for efficient cell cycle arrest...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1654129/ https://ncbi.nlm.nih.gov/pubmed/17116885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609251103 |
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