Replication of Modified Vaccinia Virus Ankara in Primary Chicken Embryo Fibroblasts Requires Expression of the Interferon Resistance Gene E3L

Highly attenuated modified vaccinia virus Ankara (MVA) serves as a candidate vaccine to immunize against infectious diseases and cancer. MVA was randomly obtained by serial growth in cultures of chicken embryo fibroblasts (CEF), resulting in the loss of substantial genomic information including many...

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Hlavní autoři: Hornemann, Simone, Harlin, Olof, Staib, Caroline, Kisling, Sigrid, Erfle, Volker, Kaspers, Bernd, Häcker, Georg, Sutter, Gerd
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC165266/
https://ncbi.nlm.nih.gov/pubmed/12857909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8394-8407.2003
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