Placental Extravillous Cytotrophoblasts Persistently Express Class I Major Histocompatibility Complex Molecules after Human Cytomegalovirus Infection

Human cytomegalovirus (HCMV) downregulates the class I major histocompatibility complexes (MHCs), HLA-A and -B, in infected fibroblasts to escape from antigen-specific cytotoxic T lymphocytes. The HCMV genes responsible for the downregulation of MHCs are US2, US3, US6, and US11, which encode type I...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Terauchi, Masakazu, Koi, Hideki, Hayano, Chikako, Toyama-Sorimachi, Noriko, Karasuyama, Hajime, Yamanashi, Yuji, Aso, Takeshi, Shirakata, Masaki
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2003
Subjects:	Virus-Cell Interactions
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165235/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12857887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.15.8187-8195.2003
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