Placental Extravillous Cytotrophoblasts Persistently Express Class I Major Histocompatibility Complex Molecules after Human Cytomegalovirus Infection

Human cytomegalovirus (HCMV) downregulates the class I major histocompatibility complexes (MHCs), HLA-A and -B, in infected fibroblasts to escape from antigen-specific cytotoxic T lymphocytes. The HCMV genes responsible for the downregulation of MHCs are US2, US3, US6, and US11, which encode type I...

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Detalhes bibliográficos
Main Authors: Terauchi, Masakazu, Koi, Hideki, Hayano, Chikako, Toyama-Sorimachi, Noriko, Karasuyama, Hajime, Yamanashi, Yuji, Aso, Takeshi, Shirakata, Masaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165235/
https://ncbi.nlm.nih.gov/pubmed/12857887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8187-8195.2003
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