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Direct Interaction with Nup153 Mediates Binding of Tpr to the Periphery of the Nuclear Pore Complex

Tpr is a 267-kDa protein forming coiled coil-dominated homodimers that locate at the nucleoplasmic side of the nuclear pore complex (NPC). The proteins that tether Tpr to this location are unknown. Moreover, the question whether Tpr itself might act as a scaffold onto which other NPC components need...

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Autors principals: Hase, Manuela E., Cordes, Volker C.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC165087/
https://ncbi.nlm.nih.gov/pubmed/12802065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-09-0620
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