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Dual Prenylation Is Required for Rab Protein Localization and Function

The majority of Rab proteins are posttranslationally modified with two geranylgeranyl lipid moieties that enable their stable association with membranes. In this study, we present evidence to demonstrate that there is a specific lipid requirement for Rab protein localization and function. Substituti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Calero, Monica, Chen, Catherine Z., Zhu, Wenyan, Winand, Nena, Havas, Karyn A., Gilbert, Penny M., Burd, Christopher G., Collins, Ruth N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC165082/
https://ncbi.nlm.nih.gov/pubmed/12802060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-11-0707
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