Toward antibody-catalyzed hydrolysis of organophosphorus poisons
We report here our preliminary results on the use of catalytic antibodies as an approach to neutralizing organophosphorus chemical weapons. A first-generation hapten, methyl-α-hydroxyphosphinate Ha, was designed to mimic the approach of an incoming water molecule for the hydrolysis of exceedingly to...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16498/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10860971/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.13.7058 |
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