Crystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-N-Acetylmuramic Acid:l-Alanine Ligase (MurC) from Haemophilus influenzae

UDP-N-acetylmuramic acid:l-alanine ligase (MurC) catalyzes the addition of the first amino acid to the cytoplasmic precursor of the bacterial cell wall peptidoglycan. The crystal structures of Haemophilus influenzae MurC in complex with its substrate UDP-N-acetylmuramic acid (UNAM) and Mg(2+) and of...

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Detalhes bibliográficos
Main Authors: Mol, Clifford D., Brooun, Alexei, Dougan, Douglas R., Hilgers, Mark T., Tari, Leslie W., Wijnands, Robert A., Knuth, Mark W., McRee, Duncan E., Swanson, Ronald V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164886/
https://ncbi.nlm.nih.gov/pubmed/12837790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.14.4152-4162.2003
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