Identification and partial characterization of a novel UDP-N-acetylenolpyruvoylglucosamine reductase/UDP-N-acetylmuramate:L-alanine ligase fusion enzyme from Verrucomicrobium spinosum DSM 4136T

The enzymes involved in synthesizing the bacterial cell wall are attractive targets for the design of antibacterial compounds, since this pathway is essential for bacteria and is absent in animals, particularly humans. A survey of the genome of a bacterium that belongs to the phylum Verrucomicrobia,...

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Detalhes bibliográficos

Principais autores:	Kubra F Naqvi, Delphine ePatin, Matthew eWheatley, Michael A Savka, Renwick eDobson, Han Ming eGan, Helene eBarreteau, Didier eBlanot, Dominique eMengin-Lecreulx, André O Hudson
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2016-03-01
coleção:	Frontiers in Microbiology
Assuntos:	Peptidoglycan Fusion enzyme MURB Bacterial cell wall MURC Verrucomicrobium spinosum
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00362/full
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