Structure based in-silico study on UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase (MurE) from Acinetobacter baumannii as a drug target against nosocomial infections

UDP-N-acetylmuramoyl-L-alanyl-d-glutamate--2,6-diaminopimelate ligase (MurE) initiates reaction by adding meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-d-glutamate, during the synthesis of murein in the cytoplasm. This enzyme is crucial for microorganisms includi...

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Prif Awduron:	Gizachew Muluneh Amera, Rameez Jabeer Khan, Amita Pathak, Ankit Kumar, Amit Kumar Singh
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2019-01-01
Cyfres:	Informatics in Medicine Unlocked
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2352914819301066
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!