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Hydrogen Peroxide Triggers Nuclear Export of Telomerase Reverse Transcriptase via Src Kinase Family-Dependent Phosphorylation of Tyrosine 707

The regulation of telomerase reverse transcriptase (TERT) plays an important role in the proliferative capacity and survival of cells. Here, we report that exogenously as well as endogenously induced oxidative stress leads to translocation of endogenous as well as overexpressed human TERT from the n...

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Detalhes bibliográficos
Main Authors: Haendeler, Judith, Hoffmann, Jörg, Brandes, Ralf P., Zeiher, Andreas M., Dimmeler, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164856/
https://ncbi.nlm.nih.gov/pubmed/12808100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4598-4610.2003
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