Rapid Turnover of Extracellular Signal-Regulated Kinase 3 by the Ubiquitin-Proteasome Pathway Defines a Novel Paradigm of Mitogen-Activated Protein Kinase Regulation during Cellular Differentiation

Mitogen-activated protein (MAP) kinases are stable enzymes that are mainly regulated by phosphorylation and subcellular targeting. Here we report that extracellular signal-regulated kinase 3 (ERK3), unlike other MAP kinases, is an unstable protein that is constitutively degraded in proliferating cel...

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में प्रकाशित:	Mol Cell Biol
मुख्य लेखकों:	Coulombe, Philippe, Rodier, Geneviève, Pelletier, Stéphane, Pellerin, Johanne, Meloche, Sylvain
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Taylor & Francis 2003
विषय:	Cell Growth and Development
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164847/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12808096/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.13.4542-4558.2003
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