Intracellular Segregation of Phosphatidylinositol-3,4,5-Trisphosphate by Insulin-Dependent Actin Remodeling in L6 Skeletal Muscle Cells

Insulin stimulates glucose uptake by recruiting glucose transporter 4 (GLUT4) from an intracellular pool to the cell surface through a mechanism that is dependent on phosphatidylinositol (PI) 3-kinase (PI3-K) and cortical actin remodeling. Here we test the hypothesis that insulin-dependent actin fil...

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Autors principals: Patel, Nish, Rudich, Assaf, Khayat, Zayna A., Garg, Rami, Klip, Amira
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Cell and Organelle Structure and Assembly
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164845/
https://ncbi.nlm.nih.gov/pubmed/12808101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4611-4626.2003
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